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BDBM235340 (3aR,5R,6aS)-5-benzyl-2- ((R)-2-hydroxy-2-(4- hydroxyphenyl)ethyl)octa- hydrocyclopenta[c]pyrrol- 5-ol::US10052306, 136::US10052306, 142

SMILES: O[C@@H](CN1C[C@H]2C[C@](O)(Cc3ccccc3)C[C@H]2C1)c1ccc(O)cc1

InChI Key: InChIKey=PFQYYQCYAUKHMU-MXNKGDRCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM235340
PNG
((3aR,5R,6aS)-5-benzyl-2- ((R)-2-hydroxy-2-(4- hydr...)
Show SMILES O[C@@H](CN1C[C@H]2C[C@](O)(Cc3ccccc3)C[C@H]2C1)c1ccc(O)cc1
Show InChI InChI=1S/C22H27NO3/c24-20-8-6-17(7-9-20)21(25)15-23-13-18-11-22(26,12-19(18)14-23)10-16-4-2-1-3-5-16/h1-9,18-19,21,24-26H,10-15H2/t18-,19+,21-,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 23.7n/an/an/an/an/an/a



CADENT THERAPEUTICS, INC.

US Patent


Assay Description
To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...


US Patent US10052306 (2018)

More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor


(Homo sapiens)
BDBM235340
PNG
((3aR,5R,6aS)-5-benzyl-2- ((R)-2-hydroxy-2-(4- hydr...)
Show SMILES O[C@@H](CN1C[C@H]2C[C@](O)(Cc3ccccc3)C[C@H]2C1)c1ccc(O)cc1
Show InChI InChI=1S/C22H27NO3/c24-20-8-6-17(7-9-20)21(25)15-23-13-18-11-22(26,12-19(18)14-23)10-16-4-2-1-3-5-16/h1-9,18-19,21,24-26H,10-15H2/t18-,19+,21-,22-/m0/s1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 23.7n/an/an/an/an/an/a



CADENT THERAPEUTICS, INC.

US Patent


Assay Description
To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...


US Patent US10052306 (2018)

More data for this
Ligand-Target Pair