BDBM23560 3-Carboxamide-coumarin deriv., 30::6-methyl-N-(4-methylphenyl)-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1ccc(NC(=O)c2cc3cc(C)ccc3oc2=O)cc1

InChI Key InChIKey=MFUWDBLYKLNULI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23560   

TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50:  2.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
University of Porto

Curated by ChEMBL
LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed