BDBM235638 (E)-1-(2,3-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-propen-1-one (12)

SMILES Oc1cccc(C(=O)\C=C\c2ccccc2O)c1O

InChI Key InChIKey=HVYFGDLINYPWGI-CMDGGOBGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235638   

TargetIntegrase(Human immunodeficiency virus 1)
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM235638((E)-1-(2,3-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of HIV1 His6-tagged integrase-human GST tagged LEDGF/p75 (373-442 residues) interaction after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences

LigandPNGBDBM235638((E)-1-(2,3-dihydroxyphenyl)-3-(2-hydroxyphenyl)-2-...)
Affinity DataIC50:  2.18E+4nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed