BDBM235727 US10117875, Example 70::US9359361, 70

SMILES O=c1c(nc2c(NCCN3CCOCC3)nc(nc2n1CCN1CCOCC1)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=AWGMTLBHLRAFLD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235727   

TargetToll-like receptor 9(Homo sapiens (Human))
Janus Biotherapeutics

US Patent
LigandPNGBDBM235727(US10117875, Example 70 | US9359361, 70)
Affinity DataIC50:  137nMAssay Description:HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 9(Homo sapiens (Human))
Janus Biotherapeutics

US Patent
LigandPNGBDBM235727(US10117875, Example 70 | US9359361, 70)
Affinity DataIC50:  137nMT: 2°CAssay Description:Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent