BDBM235932 US9365529, 20
SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)C(=O)NO)c2ccccc2n1
InChI Key InChIKey=JCBLZSWVZUEGKV-PMERELPUSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 235932
Affinity DataIC50: 3.94E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
Affinity DataIC50: 4.78E+3nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Galderma Research & Devlopment
US Patent
Galderma Research & Devlopment
US Patent
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:The TACE enzyme is an internal production (carried out according to the publication protein Eng Des Sel 2006, 19, 155-161) and is added so as to have...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Galderma Research & Devlopment
US Patent
Galderma Research & Devlopment
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Galderma Research & Devlopment
US Patent
Galderma Research & Devlopment
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The molecules are dose-response tested on the following enzymes: MMP1, MMP3, MMP9, ADAM9 and ADAM10, according to the same protocol as that described...More data for this Ligand-Target Pair