BDBM236074 US9365562, 112
SMILES Cc1nc(C)n(n1)-c1cc(nc(C)n1)N1CC(C1)c1nc2cccc(c2[nH]1)C(F)(F)F
InChI Key InChIKey=HYSGUXIEJMDSOE-UHFFFAOYSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 236074
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: >75nM ΔG°: >-9.71kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair