BDBM236112 US9365563, X1::US9878991, Compound X1

SMILES CN(C)c1ccc(NC(=O)N2CCC(=CC2)c2ncc(CO)cc2Cl)cc1C(F)(F)F

InChI Key InChIKey=FOWMHTJTYPNPDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 236112   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236112(US9365563, X1 | US9878991, Compound X1)
Affinity DataIC50:  74.4nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236112(US9365563, X1 | US9878991, Compound X1)
Affinity DataIC50:  18.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236112(US9365563, X1 | US9878991, Compound X1)
Affinity DataIC50:  74.4nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Purdue Pharma

US Patent
LigandPNGBDBM236112(US9365563, X1 | US9878991, Compound X1)
Affinity DataIC50:  18.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent