BDBM236283 US9365576, 36
SMILES COc1ccc(cc1-c1cc2C(=O)N(C(c2n1C(C)C)c1ccc(Cl)cc1)c1cc(Cl)ccc1C)C(=O)NCCS(C)(=O)=O
InChI Key InChIKey=POZXFZSLKQZFDU-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 236283
TargetCellular tumor antigen p53 [18-26]/E3 ubiquitin-protein ligase Mdm2 [2-188](Homo sapiens (Human))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.115nMT: 2°CAssay Description:Assay 2: The test is performed in white 384-well plates (Greiner Bio-One, reference 781207) in a total volume of 60 μL by adding 1 μL of compou...More data for this Ligand-Target Pair