BDBM236616 US9388136, Table 1, Compound 2:tert-Butyl N-[2-(4-{6- amino-5- [(4-fluoro- phenyl) carbonyl]-2- oxopyridin- 1(2H)-yl} phenyl)ethyl]- L-leucinate

SMILES CC(C)C[C@H](NCCc1ccc(cc1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1)C(=O)OC(C)(C)C

InChI Key InChIKey=JFHDEORVTNWJDU-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236616   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236616(US9388136, Table 1, Compound 2:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  118nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236616(US9388136, Table 1, Compound 2:tert-Butyl N-[2-(4-...)
Affinity DataIC50:  724nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent