BDBM236619 US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4-amino- 2-[(3-{4-[6-amino- 5-(2,4-difluoro- benzoyl)-2- oxopyridin- 1(2H)-yl]-3,5- difluoro- phenoxy}propyl) amino]butanoate

SMILES NCC[C@H](NCCCOc1cc(F)c(c(F)c1)-n1c(N)c(ccc1=O)C(=O)c1ccc(F)cc1F)C(=O)OC1CCCC1

InChI Key InChIKey=JPQYJAAMQYQUDL-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 236619   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Chroma Therapeutics

US Patent
LigandPNGBDBM236619(US9388136, Table 1, Compound 11:Cyclopentyl (2S)-4...)
Affinity DataIC50:  1nMpH: 7.5 T: 2°CAssay Description:The ability of compounds to inhibit p38 MAP a Kinase activity was measured in an assay performed by Upstate (Dundee UK). In a final reaction volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent