BDBM236657 US9388139, 26

SMILES CC(C)(C)C1=NN(C(C1)c1ccc(Cl)cc1)c1ccc(cc1)S(O)(=O)=O

InChI Key InChIKey=NRRGDEWQYJLZBU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 236657   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236657(US9388139, 26)
Affinity DataIC50:  7.20E+3nMAssay Description:PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236657(US9388139, 26)
Affinity DataIC50: >1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
German University

US Patent
LigandPNGBDBM236657(US9388139, 26)
Affinity DataIC50: >1.00E+5nMAssay Description:The activities of COX-1 and COX-2 were measured after the addition of arachidonic acid and incubation at 25° C. for 5 min by absorbance at 590 nm as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent