BDBM236783 US9388149, 14 (Diastereoisomer 2)::US9580412, Example 14
SMILES CN(C)C(=O)c1cccc(Nc2c(NC([C@@H]3COC(C)(C)O3)c3ccc(C)o3)c(=O)c2=O)c1O
InChI Key InChIKey=BBFTWAOVJHOJQP-BHWOMJMDSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 236783
Affinity DataIC50: 1.25E+3nMT: 2°CAssay Description:⿿PathHunter HEK293-CXCR2 or ⿿U2OS hCXCR1 β-arrestin cells (DiscoveRx Corporation) were seeded overnight at 10 000 cells/well (384-well...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+3nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the β-a...More data for this Ligand-Target Pair