BDBM236912 US9388181, 4
SMILES FC(F)(F)c1cccc(NC(=O)c2cccc(c2)N2CCc3c(C2)cnc2ccnn32)c1
InChI Key InChIKey=DFFRQPFUNWMMEA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 236912
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 192nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of PDGF-induced increases in intracellular calcium l...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.4 T: 2°CAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in 1...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMT: 2°CAssay Description:Automated FLIPR (Fluorometric Imaging Plate Reader) technology was used to screen for inhibitors of VEGF induced increases in intracellular calcium l...More data for this Ligand-Target Pair