BDBM237157 US9394307, 4-chloro-N-(5-methyl-2-{1H-pyrazolo[3,4-b]pyridine-4-carbonyl}pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES Cc1cnc(C(=O)c2ccnc3[nH]ncc23)c(NS(=O)(=O)c2ccc(Cl)c(c2)C(F)(F)F)c1

InChI Key InChIKey=VKXNYGVWEUUOMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237157   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM237157(US9394307, 4-chloro-N-(5-methyl-2-{1H-pyrazolo[3,4...)
Affinity DataIC50:  3.00E+3nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent