BDBM237521 US9393232, 2.22

SMILES C[C@@H](O)CNC1(C2CCCCC2)C(=O)Nc2ccc(cc12)-c1c(C)noc1C

InChI Key InChIKey=MYTABVRHXGACGI-BXWDTWGJSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 237521   

TargetBromodomain-containing protein 2 [1-473](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237521(US9393232, 2.22)
Affinity DataIC50:  32nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain testis-specific protein [1-397](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237521(US9393232, 2.22)
Affinity DataIC50:  42nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [1-477](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237521(US9393232, 2.22)
Affinity DataIC50:  81nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 3 [1-435](Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM237521(US9393232, 2.22)
Affinity DataIC50:  23nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent