BDBM237568 US9394263, 1n

SMILES CC[C@H](N)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC11CCCOC1

InChI Key InChIKey=TWUWLZYRYNXASN-ZVFZUAJQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237568   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237568(US9394263, 1n)
Affinity DataIC50:  4.61E+4nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [124-240](Artificial Sequence)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM237568(US9394263, 1n)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:Ten nanomolar of 6x Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent