BDBM23762 3-({4-[(4-octadecylpiperazin-1-yl)carbonyl]phenyl}methyl)-4,5-dihydro-1,2,4-oxadiazol-5-one::PMS 1062 piperazine deriv., 26c

SMILES CCCCCCCCCCCCCCCCCCN1CCN(CC1)C(=O)c1ccc(Cc2nc(=O)o[nH]2)cc1

InChI Key InChIKey=KCTPIHXVLNNXIG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23762   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23762(3-({4-[(4-octadecylpiperazin-1-yl)carbonyl]phenyl}...)
Affinity DataIC50:  800nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Universite Paris 7-Denis Diderot

LigandPNGBDBM23762(3-({4-[(4-octadecylpiperazin-1-yl)carbonyl]phenyl}...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant group 2A phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM23762(3-({4-[(4-octadecylpiperazin-1-yl)carbonyl]phenyl}...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of porcine group 1B phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2, major isoenzyme(Sus scrofa (pig))
Universit£

Curated by ChEMBL
LigandPNGBDBM23762(3-({4-[(4-octadecylpiperazin-1-yl)carbonyl]phenyl}...)
Affinity DataIC50: >1.00E+5nMAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue as the substrate. The increase in fluorescence (ex @342 nm and em@388 nm) of the enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed