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BDBM237687 US10052306, 233::rac-(3aR,5r,6aS)-5-(2,4- difluorobenzyl)-2-(2- hydroxy-2-(5- hydroxypyridin-2- yl)ethyl)octahydrocyclo- penta[c]pyrrol-5-ol

SMILES: OC(CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3F)C[C@H]2C1)c1ccc(O)cn1

InChI Key: InChIKey=VVIBJRKWDJTQAO-PCTSKLMYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237687   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens)
BDBM237687
PNG
(US10052306, 233 | rac-(3aR,5r,6aS)-5-(2,4- difluor...)
Show SMILES OC(CN1C[C@H]2C[C@](O)(Cc3ccc(F)cc3F)C[C@H]2C1)c1ccc(O)cn1
Show InChI InChI=1S/C21H24F2N2O3/c22-16-2-1-13(18(23)5-16)6-21(28)7-14-10-25(11-15(14)8-21)12-20(27)19-4-3-17(26)9-24-19/h1-5,9,14-15,20,26-28H,6-8,10-12H2/t14-,15+,20?,21-
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 29.9n/an/an/an/an/an/a



CADENT THERAPEUTICS, INC.

US Patent


Assay Description
To each well of the plate, 10 μL test compound, control (MK801) or HHnoCa buffer was added to a final concentration of 10 μM with a final c...


US Patent US10052306 (2018)

More data for this
Ligand-Target Pair