BDBM238181 US9394303, 8

SMILES Cc1nn(Cc2ccc(Oc3ccccc3)cc2)c2nc(cc(C(O)=O)c12)-c1ccco1

InChI Key InChIKey=GYXFBYPMROKCLN-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238181   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mus musculus (Mouse))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM238181(US9394303, 8)
Affinity DataKi:  290nM ΔG°:  -8.91kcal/mole IC50:  1.52E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Mus musculus (Mouse))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM238181(US9394303, 8)
Affinity DataKi: >4.00E+3nM ΔG°: >-7.36kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Mus musculus (Mouse))
The Regents Of The University Of Michigan

US Patent
LigandPNGBDBM238181(US9394303, 8)
Affinity DataKi: >5.00E+3nM ΔG°: >-7.23kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent