BDBM239061 US10227295, Compound 9c::US9409858, 9c::US9751832, Compound 9c::US9956192, Compound 9c

SMILES Cc1cc(NC(=O)NCc2ccc(cc2)C(=O)NO)no1

InChI Key InChIKey=RBSHAWCOAAORSM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 239061   

TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  1.00E+3nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  6.90nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  1.00E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  6.90nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  1.00E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  6.90nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  1.00E+3nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

US Patent
LigandPNGBDBM239061(US10227295, Compound 9c | US9409858, 9c | US975183...)
Affinity DataIC50:  6.90nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent