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BDBM23936 1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]benzene::trans-Stilbene Derivative, 4i

SMILES: FC(F)(F)c1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1

InChI Key: InChIKey=ISPYNXGXZRLLHM-OWOJBTEDSA-N

Data: 2 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23936   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aryl Hydrocarbon Receptor (AhR)


(Oryctolagus cuniculus (rabbit))
BDBM23936
PNG
(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Show SMILES FC(F)(F)c1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1
Show InChI InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1+
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
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PC cid
PC sid
UniChem

Similars

Article
PubMed
0.200 -12.3n/an/an/an/an/a7.64



Institut Claudius Regaud



Assay Description
Cytosols from rabbit liver were incubated with [3H]-TCDD and 12 concentrations of unlabeled test ligands. IC50 values were determined using the itera...


J Med Chem 48: 287-91 (2005)


Article DOI: 10.1021/jm0498194
BindingDB Entry DOI: 10.7270/Q2WM1BQT
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM23936
PNG
(1,3-dichloro-5-[(E)-2-[4-(trifluoromethyl)phenyl]e...)
Show SMILES FC(F)(F)c1ccc(\C=C\c2cc(Cl)cc(Cl)c2)cc1
Show InChI InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Institut Claudius Regaud



Assay Description
Cytosols from MCF-7 cells expressed ER-alpha isoform were incubated with [3H]-estradiol and eight concentrations of unlabeled test ligands. IC50 val...


J Med Chem 48: 287-91 (2005)


Article DOI: 10.1021/jm0498194
BindingDB Entry DOI: 10.7270/Q2WM1BQT
More data for this
Ligand-Target Pair