BDBM239932 US9403767, 115

SMILES CN(C)C1(CCC(CC1)(N(C)Cc1cccc(c1)C(F)(F)F)c1ccccc1)c1ccccc1

InChI Key InChIKey=FGTDQTXXPGHWDE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 239932   

TargetNociceptin receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM239932(US9403767, 115)
Affinity DataKi:  1.17E+3nMpH: 7.4Assay Description:The compounds were examined with membranes of recombinant CHO-ORL 1 cells in a receptor binding assay with 3H-nociceptin/orphanin FQ. This test syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM239932(US9403767, 115)
Affinity DataKi:  1.67E+3nM ΔG°:  -7.88kcal/moleT: 2°CAssay Description:The affinity to the human μ-opiate receptor was determined in a homogeneous preparation in microtiter plates. For this, dilution series of the res...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent