BDBM24025 (2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]butanoic acid::CHEMBL382117::biphenylsulfonamide carboxylate, 2

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=BGKNBDGHNBOSGD-MRXNPFEDSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24025   

LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  3.00E+3nMpH: 7.5 T: 2°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aggrecanase1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0380nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0620nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed