BDBM241181 US10479788, Example 23::US11046688, Example 23::US9409907, 23

SMILES Cn1cc(cn1)-c1ccc(Nc2cc3c(cccc3cn2)-c2cnn(C)c2)c(Cl)c1

InChI Key InChIKey=AFYTVYVYMOQWPI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 241181   

TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241181(US10479788, Example 23 | US11046688, Example 23 | ...)
Affinity DataIC50:  225nMpH: 7.0 T: 2°CAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241181(US10479788, Example 23 | US11046688, Example 23 | ...)
Affinity DataIC50:  225nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM241181(US10479788, Example 23 | US11046688, Example 23 | ...)
Affinity DataIC50:  225nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent