BDBM24143 8-ethyl-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-tetrahydroisoquinoline-2-carboxamide::tetrahydroisoquinoline (THIQ), 47

SMILES CCc1cccc2C(CN(Cc12)C(=O)N(C)C)c1cccc(O)c1

InChI Key InChIKey=SNCKDOOXTVGANV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24143   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Bristol-Myers Squibb

LigandBDBM24143(8-ethyl-4-(3-hydroxyphenyl)-N,N-dimethyl-1,2,3,4-t...)Copy SMILESCopy InChI

Affinity DataIC50:  344nMAssay Description:ATPase assays with Eg5 motor domain protein were performed using Kinase-Glo Luminescent Kit as described by the manufacturer (Promega).More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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