BDBM242020 US9415055, N-[2-(4-Chloro-phenyl)-2-(4,4-difluoro-piperidin-1-yl)-ethyl]-2,3-dimethyl-benzamide::US9593105, 21

SMILES Cc1cccc(C(=O)NCC(N2CCC(F)(F)CC2)c2ccc(Cl)cc2)c1C

InChI Key InChIKey=JTQVHGRELGUEGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 242020   

TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242020(US9415055, N-[2-(4-Chloro-phenyl)-2-(4,4-difluoro-...)
Affinity DataIC50:  3.60nMAssay Description:Cell culture: 293 HEK cells, stably transfected with plasmids capable of expressing human P2X7 receptor, were cultured by standard methods. Cells wer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetP2X purinoceptor 7(Homo sapiens (Human))
H. Lundbeck

US Patent
LigandPNGBDBM242020(US9415055, N-[2-(4-Chloro-phenyl)-2-(4,4-difluoro-...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), NaH2PO42H2O (9.6 mM), HEPES (25 mM), sucrose (280...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent