BDBM243354 4-{5-[3-(4-Phenyl- pyrimidin-2-ylamino)- phenyl]-oxazol-2-yl}-4,7- diaza-spiro[2.5]octan-8- one::US10053455, 010

SMILES O=C1NCCN(c2ncc(o2)-c2cccc(Nc3nccc(n3)-c3ccccc3)c2)C11CC1

InChI Key InChIKey=WJQNGZJQWVTNLJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 243354   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Ab Science

US Patent
LigandPNGBDBM243354(4-{5-[3-(4-Phenyl- pyrimidin-2-ylamino)- phenyl]-o...)
Affinity DataIC50: <500nMpH: 7.8 T: 2°CAssay Description:SYK kinase was purified as a full length protein in a baculovirus system near homogeneity. All kinase assays were performed with the Kinase TK (tyros...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent