BDBM243469 US9427440, 17
SMILES COc1ccc2-c3c(C4CCCCC4)c4ccc5cc4n3CC(=C(C)c2c1)C(=O)N(C)CCCCN(C)S(=O)(=O)NC5=O
InChI Key InChIKey=BYYIYLUYDUVZDT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 243469
TargetGenome polyprotein [1027-3010](Hepatitis C virus genotype 1b (strain HC-J4) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataEC50: 170nMAssay Description:The assay utilized the stably transfected cell line Huh-7 luc/neo (hereafter referred to as Huh-Luc). This cell line harbors an RNA encoding a bicist...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataKon: 0.000160M-1s-1 Koff: 8.70E+3s-1pH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair
TargetGenome polyprotein [2420-3010](Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Ireland
US Patent
Janssen Ireland
US Patent
Affinity DataKd: 18nMpH: 7.4 T: 2°CAssay Description:All measurements were performed on a Biacore T100 instrument (GE Healthcare). The purified HIS6-tagged NS5BΔC21 polymerases were immobilized us...More data for this Ligand-Target Pair