BDBM24355 N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)phenyl]octanediamide::Triazole Ligand, 12c

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cnnn1-c1ccccc1

InChI Key InChIKey=OSBJPHXXKNVNGT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24355   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  70.5nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  146nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  3.5nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  518nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  55.7nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
University Of Illinois At Chicago

LigandPNGBDBM24355(N-hydroxy-N'-[4-(1-phenyl-1H-1,2,3-triazol-5-yl)ph...)
Affinity DataIC50:  12nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed