BDBM244137 US9428492, 10::US9428492, 10a::US9428492, 10b

SMILES CC(O)c1nc(C)nn1-c1cc(nc(n1)C1CC1)N1CC(C1)c1nc2ccccc2n1C

InChI Key InChIKey=PUPQIAGHGHGYRI-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244137   

LigandPNGBDBM244137(US9428492, 10 | US9428492, 10a | US9428492, 10b)
Affinity DataKi:  0.130nM ΔG°:  -13.5kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM244137(US9428492, 10 | US9428492, 10a | US9428492, 10b)
Affinity DataKi:  0.210nM ΔG°:  -13.2kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM244137(US9428492, 10 | US9428492, 10a | US9428492, 10b)
Affinity DataKi:  0.390nM ΔG°:  -12.8kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent