BDBM244210 (5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidin-6(7h)-yl)(3,3,4-trimethylpiperazin-1-yl)methanone::US9546173, cmpd 149

SMILES CN1CCN(CC1(C)C)C(=O)N1Cc2nc(Nc3ccccc3)ncc2C1(C)C

InChI Key InChIKey=BKDJDBPDISZFBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244210   

TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244210((5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyr...)
Affinity DataIC50:  611nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM244210((5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyr...)
Affinity DataIC50:  3.77E+4nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent