BDBM244290 US9550763, Compound I-038

SMILES NC(=O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)n1

InChI Key InChIKey=XJQQDUVNNYSCLN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 244290   

TargetP2X purinoceptor 3(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM244290(US9550763, Compound I-038)
Affinity DataIC50:  2nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent