BDBM244751 US10226449, cpd 361::US9428502, 361

SMILES COCCc1nc(Cl)c([nH]1)-c1cc(ccc1C)C(=O)N1CC(C1)c1ccc(cc1)C#N

InChI Key InChIKey=SEIWGLRQKXGYFV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244751   

TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM244751(US10226449, cpd 361 | US9428502, 361)
Affinity DataIC50:  13nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM244751(US10226449, cpd 361 | US9428502, 361)
Affinity DataIC50:  13nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent