BDBM244758 US10226449, cpd 368::US9428502, 368
SMILES Cc1nc(c([nH]1)-c1cc(ccc1C)C(=O)N1CC(F)(C1)c1ccc(cc1)C#N)C(F)(F)F
InChI Key InChIKey=BWQFZTFMIMYQBW-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 244758
Affinity DataIC50: 12nMAssay Description:FASN activity of the SKBr3 cell extract was determined by measuring either NADPH oxidation or the amount of thiol-containing coenzyme A (CoA) release...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMT: 2°CAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair