BDBM24514 4-nitrophenoxyphosphonic acid::4-nitrophenyl phosphate::CHEMBL24231::p-nitrophenyl phosphate

SMILES OP(O)(=O)Oc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=XZKIHKMTEMTJQX-UHFFFAOYSA-N

Data  5 IC50

PDB links: 8 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 24514   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Affinity DataIC50:  1.00E+6nMAssay Description:The compound was evaluated for its binding affinity towards phosphotyrosine binding pocket of Src protein tryrosine kinase SH2 domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Affinity DataIC50:  330nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 1 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerum paraoxonase/arylesterase 1(Homo sapiens (Human))
The University Of Birmingham

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Affinity DataIC50:  1.85E+7nMAssay Description:Inhibitory activity against human serum paraoxonase (PON1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of esterase activity of mouse carbonic anhydrase 13 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM24514(4-nitrophenoxyphosphonic acid | 4-nitrophenyl phos...)
Affinity DataIC50:  63nMAssay Description:Inhibition of esterase activity of human carbonic anhydrase 2 by CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed