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BDBM245151 US9428460, 7

SMILES: Cc1cc(no1)C(=O)NC[C@H]1CC[C@@H](CC1)Oc1ccnc2c(F)cccc12

InChI Key: InChIKey=SNDPSGJDCPSJLQ-SHTZXODSSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 245151   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen receptor


(Homo sapiens (Human))
BDBM245151
PNG
(US9428460, 7)
Show SMILES Cc1cc(no1)C(=O)NC[C@H]1CC[C@@H](CC1)Oc1ccnc2c(F)cccc12
Show InChI InChI=1S/C21H22FN3O3/c1-13-11-18(25-28-13)21(26)24-12-14-5-7-15(8-6-14)27-19-9-10-23-20-16(19)3-2-4-17(20)22/h2-4,9-11,14-15H,5-8,12H2,1H3,(H,24,26)/t14-,15-
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 480n/an/an/an/an/a37



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
For determining the androgen receptor-dependent transcription, a cellular assay system was used, consisting of PC-3 cells (Kaighn et al., Invest. Uro...


US Patent US9428460 (2016)


BindingDB Entry DOI: 10.7270/Q25719Z7
More data for this
Ligand-Target Pair