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BDBM245155 US9428460, 11

SMILES: Cc1cc(no1)C(=O)NC[C@H]1CC[C@@H](CC1)Oc1ccnc2ccccc12

InChI Key: InChIKey=ZXIJUQZCPPJBSO-WKILWMFISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 245155   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Androgen receptor (AR)


(Homo sapiens (Human))
BDBM245155
PNG
(US9428460, 11)
Show SMILES Cc1cc(no1)C(=O)NC[C@H]1CC[C@@H](CC1)Oc1ccnc2ccccc12
Show InChI InChI=1S/C21H23N3O3/c1-14-12-19(24-27-14)21(25)23-13-15-6-8-16(9-7-15)26-20-10-11-22-18-5-3-2-4-17(18)20/h2-5,10-12,15-16H,6-9,13H2,1H3,(H,23,25)/t15-,16-
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 210n/an/an/an/an/a37



BAYER PHARMA AKTIENGESELLSCHAFT

US Patent


Assay Description
For determining the androgen receptor-dependent transcription, a cellular assay system was used, consisting of PC-3 cells (Kaighn et al., Invest. Uro...


US Patent US9428460 (2016)


BindingDB Entry DOI: 10.7270/Q25719Z7
More data for this
Ligand-Target Pair