BDBM245251 US9428500, 45

SMILES COc1ccccc1C#Cc1ccnc2n(C)c3ccc(cc3c12)-c1ccc(cc1)N1CCN(C)CC1

InChI Key InChIKey=LGWYYNUBQSJASZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245251   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245251(US9428500, 45)
Affinity DataIC50:  910nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Universita Degli Studi Di Milano—Bicocca

US Patent
LigandPNGBDBM245251(US9428500, 45)
Affinity DataIC50:  3.80E+3nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent