BDBM24530 (2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one::Benzisothiazole analogue, 17

SMILES COc1cc(\C=C2\S\C(NC2=O)=N/c2nsc3ccccc23)ccc1O

InChI Key InChIKey=MVMPYCDFQNONAY-OQLLNIDSSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24530   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Aristotle University

LigandPNGBDBM24530((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-hydro...)
Affinity DataKi:  9.08E+4nM ΔG°:  -5.51kcal/molepH: 7.0 T: 2°CAssay Description:SHP-2 inhibitory activity was tested using human recombinant GST-fusion SHP-2 (Calbiochem). Test compound was preincubated with enzyme mixture before...More data for this Ligand-Target Pair
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