BDBM24565 2-({4-chloro-6-[(quinolin-6-ylmethyl)amino]pyrimidin-2-yl}sulfanyl)octanoic acid::CHEMBL518643::Pirinixic acid-based compound, 6g

SMILES CCCCCCC(Sc1nc(Cl)cc(NCc2ccc3ncccc3c2)n1)C(O)=O

InChI Key InChIKey=GFVINPFCXHFGPG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24565   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM24565(2-({4-chloro-6-[(quinolin-6-ylmethyl)amino]pyrimid...)
Affinity DataIC50:  3.10E+4nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM24565(2-({4-chloro-6-[(quinolin-6-ylmethyl)amino]pyrimid...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant COX2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM24565(2-({4-chloro-6-[(quinolin-6-ylmethyl)amino]pyrimid...)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed