BDBM245826 US9428514, 14

SMILES CCOc1cc(=O)n(C)cc1-c1cc(NCCCC(=O)OC)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=XMFRYHDSTAXQPH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245826   

TargetBromodomain-containing protein 4 [352-457](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245826(US9428514, 14)
Affinity DataKi:  61.6nM ΔG°:  -9.83kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245826(US9428514, 14)
Affinity DataKi:  248nM ΔG°:  -9.01kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent