BDBM245849 US9428514, 37

SMILES CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cc2ccc(Oc3ccccc3)cc2)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=ITZDGUNXXRKGPS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245849   

TargetBromodomain-containing protein 4 [352-457](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245849(US9428514, 37)
Affinity DataKi:  69.4nM ΔG°:  -9.76kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245849(US9428514, 37)
Affinity DataKi:  1.69E+3nM ΔG°:  -7.87kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent