BDBM245859 US9428514, 47

SMILES CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)CNC(=O)c2ccccc2)ccc1Oc1ccc(F)cc1F

InChI Key InChIKey=JAXXWPTYVGQVHE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 245859   

TargetBromodomain-containing protein 4 [352-457](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245859(US9428514, 47)
Affinity DataKi:  56.7nM ΔG°:  -9.88kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [57-168](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM245859(US9428514, 47)
Affinity DataKi:  226nM ΔG°:  -9.06kcal/molepH: 6.0 T: 2°CAssay Description:Assay method B: Compound dilution series were prepared in DMSO via an approximately 3-fold serial dilution from one of the following: 0.47 mM to 7.8 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent