BDBM246499 (1E,4E,6E)-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one (19)

SMILES Oc1ccc(\C=C\C=C\C(=O)\C=C\c2ccc(O)cc2)cc1

InChI Key InChIKey=PALMCMYYFAHUGA-BPTNNVFMSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246499   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM246499((1E,4E,6E)-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatri...)
Affinity DataKi:  3.34E+3nM ΔG°:  -7.77kcal/mole IC50:  1.64E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246499((1E,4E,6E)-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatri...)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246499((1E,4E,6E)-1,7-bis(4-hydroxyphenyl)-1,4,6-heptatri...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed