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BDBM246596 TIM inhibitor, 1

SMILES: Cc1ccc(cc1)-c1nsc(=O)[nH]1

InChI Key: InChIKey=XXKKENPLAPXKFL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 246596   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Triosephosphate isomerase (TIM)


(Homo sapiens (Human))
BDBM246596
PNG
(TIM inhibitor, 1)
Show SMILES Cc1ccc(cc1)-c1nsc(=O)[nH]1
Show InChI InChI=1S/C9H8N2OS/c1-6-2-4-7(5-3-6)8-10-9(12)13-11-8/h2-5H,1H3,(H,10,11,12)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.00E+5n/an/an/an/a7.437



Universidad de la República



Assay Description
The reaction mixture (1 mL, pH 7.4) contained 100mM triethanolamine, 10mM EDTA, 0.2mM NADH, 1mM glyceraldehyde 3-phosphate (GAP) and 0.9 units of a-g...


J Enzyme Inhib Med Chem 29: 198-204 (2014)


Article DOI: 10.3109/14756366.2013.765415
BindingDB Entry DOI: 10.7270/Q27S7MPS
More data for this
Ligand-Target Pair