BDBM246604 DNA topoisomerase inhibitor, 6

SMILES Brc1ccc(NC(=S)NNC(=O)C2CCNCC2)cc1

InChI Key InChIKey=XEDFRPHNRACQIT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246604   

TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Medical University

LigandPNGBDBM246604(DNA topoisomerase inhibitor, 6)
Affinity DataIC50:  2.50E+5nMpH: 7.8 T: 2°CAssay Description:Supercoiled pHOT1 DNA (0.5 μg) was incubated with four units of human topoisomerase I in relaxation buffer (10mM Tris-HCl (pH 7.8), 1mM EDTA, 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Medical University

LigandPNGBDBM246604(DNA topoisomerase inhibitor, 6)
Affinity DataIC50:  2.50E+5nMpH: 7.8 T: 2°CAssay Description:Supercoiled pHOT1 DNA (0.5 μg) was incubated with four units of human topoisomerase I in relaxation buffer (10mM Tris-HCl (pH 7.8), 1mM EDTA, 0.15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed