BDBM246607 HER2/EGFR dual kinase inhibitor, 5d

SMILES Fc1ccc(cc1)-c1cc([nH]c(=N)c1C#N)-c1ccc(Nc2ncnc3ccccc23)cc1

InChI Key InChIKey=LUNPOMNMCATHCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246607   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Msa University

LigandPNGBDBM246607(HER2/EGFR dual kinase inhibitor, 5d)
Affinity DataIC50:  3.98E+3nMAssay Description:Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Msa University

LigandPNGBDBM246607(HER2/EGFR dual kinase inhibitor, 5d)
Affinity DataIC50:  2.09E+3nMAssay Description:Protein kinase assays were performed at ambient temperature for 20-40 min (depending on the target) in a final volume of 25 μl according to the fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed