BDBM24720 5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{11,16}]heptadeca-1(10),2,5,11,13,15-hexaene::tetrahydropyrazolocycloheptaindole, 23

SMILES Cc1[nH]nc-2c1CCCc1c-2[nH]c2ccccc12

InChI Key InChIKey=HEOHDCAIYRDHHZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24720   

TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24720(5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24720(5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  42nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed