BDBM248106 IMPDH II inhibitor, 23

SMILES CCC(CC#N)OC(=O)N[C@@H](C)c1cccc(NC(=O)Nc2ccc3cc(OC)c(OC)cc3c2)c1

InChI Key InChIKey=CUALRBGBFLPCON-NVHKAFQKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 248106   

TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Nycomed

LigandPNGBDBM248106(IMPDH II inhibitor, 23)
Affinity DataIC50: <3.00E+4nMpH: 8.0 T: 2°CAssay Description:The assay was performed in a 100 μL final volume in 96-well UV plates (Costar, 3635) with a reaction buffer composed of 50 mM Tris-HCl (pH 8.0), 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed