BDBM24928 2-amino-isoxazolopyridine, 4::3-(3-methylphenyl)-N-[(1S)-1-phenylethyl]pyrido[4,3-d][1,2]oxazol-5-amine

SMILES C[C@H](Nc1cc2c(noc2cn1)-c1cccc(C)c1)c1ccccc1

InChI Key InChIKey=RMKFZACOOVWLAE-HNNXBMFYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 24928   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50:  549nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50:  1.45E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed